Friday, June 22, 2012

NSAID and Skin Cancer


NSAIDs are non-steroidal anti-inflammatory drugs, such as aspirin and ibuprofen. So if you use aspirin, you are using a non-steroidal drug, probably to reduce inflammation. Most of us, including this Cape Coral plastic surgeon, do

Now, an article appearing in the journal “Cancer” shows nsaids may decrease the risk of developing malignant melanoma and squamous cell carcinoma.  The study was huge and was done in Denmark.  They compared people's incidence of these 2 types of skin cancer and whether or not those are people who filled more than two scripts for nsaids. Those who did showed a 15% decrease in squamous cell skin cancer and a 13% decrease in melanoma.  

The mechanism is not fully understood.  The nsaids target a certain enzyme also seen in these skin cancers.

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